Inactive Obese At Risk Of Heart Disease & Diabetes

Inactive Obese At Risk Of Heart Disease & Diabetes
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Sedentary behaviour associated with poor cardiovascular health, diabetes in people with severe obesity

Sedentary behaviour is associated with poor cardiovascular health and diabetes in adults with severe obesity, independent of how much exercise they perform, a University of Pittsburgh Graduate School of Public Health-led study showed for the first time.

The finding, published online and scheduled for the March issue of the journal Preventive Medicine, could be used to design and test programs for adults with severe obesity that emphasize reducing time spent sitting, rather than immediately working toward increased moderate- to vigorous-intensity physical activity or exercise, such as brisk walking. In the U.S., 15 percent of adults have severe obesity, placing them at high risk of cardiovascular and metabolic disease, and premature mortality.

“Adults with severe obesity often have difficulty following national guidelines to participate in at least 30 minutes per day of moderate- to vigorous-intensity physical activity for health benefits,” said lead author Wendy C. King, Ph.D., associate professor in the Department of Epidemiology at Pitt Public Health. “Our findings suggest that replacing sedentary behaviour, like watching television or sitting at the computer, with low-intensity physical activities, such as light housework or going for a casual stroll, may improve cardiometabolic health in this population.”

In addition, Dr King and her colleagues determined that defining “sedentary time” as 10 minutes or more without walking yielded stronger associations between sedentary behaviour and cardiometabolic health compared to allowing sedentary time to be as short as one minute, which has been the norm in the field.

“This is important because an accurate assessment of sedentary behaviour is crucial to being able to evaluate if and how this behaviour is related to health outcomes. If our estimate of sedentary behaviour is poor, we may not detect true associations,” said Dr King.

She and her colleagues followed 927 patients participating in the Longitudinal Assessment of Bariatric Surgery-2, a prospective study of patients undergoing weight-loss surgery at one of 10 different hospitals across the U.S. For a one-week period before surgery, the research team measured the participants’ activity–or lack of activity–using monitors that tracked the number of steps taken each minute.

For every hour per day participants spent in sedentary bouts of at least 10 minutes, their odds of having diabetes increased by 15 percent, metabolic syndrome by 12 percent and elevated blood pressure by 14 percent, and their waist circumference was a half inch larger, after adjusting for their sex, age, household income, smoking status, alcohol use, depressive symptoms, body mass index (BMI) and time spent in moderate- to vigorous-intensity physical activity.

“These findings indicate the importance of investigating sedentary behaviour as a distinct health risk behaviour, not simply lack of moderate- to vigorous-intensity physical activity, among adults with severe obesity,” said Dr King. “This ultimately may inform physical activity guidelines for this special population.”

Future research is needed to determine whether replacing the sedentary behaviour with low-intensity physical activity is an effective approach to preventing and managing cardiovascular and metabolic diseases in adults with severe obesity, and evaluate strategies to help this population make such lifestyle changes.


Source:

University of Pittsburgh Schools of the Health Sciences